Celyra Bio is a start-up project set to solve the limitations in exosome production, by betting on pluripotent stem cells and machine learning optimization. Our platform combines stem cells from different species to circumvent regulatory hurdles across regions and to unlock novel exosome bioactive profiles.
The plan is to target dermo-cosmetics first, as they offer a faster market entry and an opportunity to de-risk the business before expanding to the field of therapeutics.
The project is currently being incubated at Genopole, in Evry-Courcouronnes, and the company has not been incorporated yet.
We are seeking a Co-founder and CTO/CMO to architect, build, and scale the operational backbone of the company from lab setup to GMP-aligned production. Keep in mind that the project is currently at a very early stage and still requires early bioprocess development.
Responsibilities
-Utilizing problem-solving skills to address complex challenges and drive continuous improvement
-Designing and implementing scalable manufacturing processes for pluripotent stem cell-derived exosomes.
-Leading development of upstream (suspension culture, expansion) and downstream (isolation, purification, characterization) workflows.
-Building a GMP-aligned bioprocess infrastructure and overseeing technology transfer to pilot and commercial-scale production.
-Overseeing product safety and stability testing frameworks.
-Identifying and managing suppliers for raw materials, media, reagents, and consumables.
-Recruiting and managing technical and operations team.
The ideal candidate should have several of the following:
-PhD or MS in Bioengineering, Bioprocess Engineering, or related field.
-Experience as a founder or early employee in a life sciences startup, ideally in the field of innovative dermo-cosmetics.
-Experience in biologics manufacturing, cell therapy, exosomes, or related advanced bioprocessing.
-Experience working in or with cosmetic, biotech, or advanced ingredient companies.
-Direct experience working with pluripotent stem cells (iPSCs or ESCs) is strongly preferred.
-Strong knowledge of extracellular vesicle isolation and characterization methods.
-Proven experience building or scaling GMP or GMP-like manufacturing operations.
-Familiarity with QC/QA systems, batch records, and regulatory documentation.
-Demonstrated cost modeling and COGS optimization experience.
-Familiarity with contract manufacturing (CDMOs) and supplier ecosystems.
-Existing network in dermo-cosmetics or regenerative aesthetics is a plus.
-Ownership mindset, resilience and integrity.
Location and Language
-Based in France or able to relocate
-Professional proficiency in English
How to Apply
If you are excited about joining, please send an introductory email along with your relevant experience to victor@celyrabio.com